The Relationship Between Depression and Cognitive Deterioration in Elderly Persons
DOI:
https://doi.org/10.1590/0102.3772e37413%20Keywords:
Depression, Cognitive decline, Prevalence, Psychosocial factors, Cross-sectional studyAbstract
The objective of this research is to describe the relationship between depressive disorder and cognitive deterioration in residentialized elderly people. This is a descriptive and correlational study with 70 elderly. The variables have been assessed with a Psychosocial Variables Questionnaire, CAMCOG and GDS. Depression was significantly correlated with cognitive level in the non-assisted elderly sample (r=0.471, p=0.004). Participants’ age is negatively associated with the score obtained in the CAMCOG of non-assisted sample (r=-0.352, p=0.038). Depression is more frequent in institutions that care for older people when they are more dependent.
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Alexopoulos, G. S. (2005). Depression in the Elderly. The Lancet, 365(9475), 1961-1970. https://doi.org/10.1016/S0140-6736(05)66665-2
Almomani, F. M., & Bani-Issa, W. (2017). The Incidence of Depression among Residents of Assisted Living: Prevalence and Related Risk Factors. Clinical Intervention in Aging, 12, 1645-1653. https://doi.org/10.2147/CIA.S147436
Ames, D. (1991). Epidemiological Studies of Depression Among The Elderly in Residential and Nursing Homes. International Journal of Geriatric Psychiatry, 6(6), 347-354. https://doi.org/10.1002/gps.930060604
Austin, M.-P., Mitchell, P., & Goodwin, G. M. (2001). Cognitive Deficits in Depression: Possible Implications for Functional Neuropathology. The British Journal of Psychiatry, 178(3), 200-206. https://doi.org/10.1192/bjp.178.3.200
Baladón, L., Fernández, A., Rubio-Valera, M., Cuevas-Esteban, J., Palao, D. J., Bellon, J. A., & Serrano-Blanco, A. (2015). Prevalence of Mental Disorders in Non-Demented Elderly People in Primary Care. International Psychogeriatrics, 27(5), 757-768. https://doi.org/10.1017/S1041610215000575
Banaszak-Holl, J., Liang, J., Quinones, A., Cigolle, C., Lee, I.-C., & Verbrugge, L. M. (2011). Trajectories of Functional Change Among Long Stayers in Nursing Homes: Does Baseline Impairment Matter? Journal of Aging and Health, 23(5), 862-882. https://doi.org/10.1177/0898264311399759
Beekman, A. T., de Beurs, E., van Balkom, A. J., Deeg, D. J., van Dyck, R., & van Tilburg, W. (2000). Anxiety and Depression in Later Life: Co-Occurrence and Communality of Risk Factors. American Journal of Psychiatry, 157(1), 89-95. https://doi.org/10.1176/ajp.157.1.89
Boi, R., Racca, L., Cavallero, A., Carpaneto, V., Racca, M., Dall'Acqua, F., Richetti, M., Alida, S., & Odetti, P. (2012). Hearing Loss and Depressive Symptoms in Elderly Patients. Geriatrics & Gerontology International, 12(3), 440-445. https://doi.org/10.1111/j.1447-0594.2011.00789.x
Bürge, E., von Gunten, A., & Berchtold, A. (2013). Factors Favoring a Degradation or An Improvement in Activities of Daily Living (ADL) Performance Among Nursing Home (NH) Residents: A Survival Analysis. Archives of Ggerontology and Ggeriatrics, 56(1), 250-257. https://doi.org/10.1016/j.archger.2012.09.001
Burhanullah, M. H., Tschanz, J. T., Peters, M. E., Leoutsakos, J.-M., Matyi, J., Lyketsos, C. G., Nowrangi, M. D., & Rosenberg, P. B. (2020). Neuropsychiatric Symptoms As Risk Factors for Cognitive Decline in Clinically Normal Older Adults: The Cache County Study. The American Journal of Geriatric Psychiatry, 28(1), 64-71. https://doi.org/10.1016/j.jagp.2019.03.023
Camacho-Conde, J. A. (2009). Síndromes Geriátricos [Geriatric Syndromes]. Albay Ediciones S.L.
Camacho-Conde, J. A. (2019). Enfermedad de Parkinson: Implicaciones Autonómicas y Afectivas [Parkinson's Disease: Autonomic and Affective Implications]. Wanceulen.
Cerdá, R., López-Torres, J., Fernández, C., López, M., & Otero, A. (1997). Depresión en Personas Ancianas. Factores Asociados [Depression in Elderly People. Associated Factors]. Atención Primaria, 19(1), 12-17.
Cosh, S., Helmer, C., Delcourt, C., Robins, T. G., & Tully, P. J. (2019). Depression in Elderly Patients with Hearing Loss: Current Perspectives. Clinical Interventions in Aging, 14, 1471. http://doi.org/10.2147/CIA.S195824
Chan, C. K., Soldan, A., Pettigrew, C., Wang, M.-C., Wang, J., Albert, M. S., Rosenberg, P. B., & BIOCARD Research Team. (2019). Depressive Symptoms in Relation to Clinical Symptom Onset of Mild Cognitive Impairment. International Psychogeriatrics, 31(4), 561-569. https://doi.org/10.1017/S1041610218001138
Chou, K. L., & Chi, I. (2004). Combined Effect of Vision and Hearing Impairment on Depression in Elderly Chinese. International Journal of Geriatric Psychiatry, 19(9), 825-832. https://doi.org/10.1002/gps.1174
Dean, K., Oulhaj, A., Zamboni, G., Dejager, C. A., & Wilcock, G. K. (2014). Role of Depression in Predicting Time to Conversion to Mild Cognitive Impairment. The American Journal of Geriatric Psychiatry, 22(7), 727-734. https://doi.org/10.1016/j.jagp.2012.12.025
Dickinson, W. J., Potter, G. G., Hybels, C. F., McQuoid, D. R., & Steffens, D. C. (2011). Change in Stress and Social Support as Predictors of Cognitive Decline in Older Adults With and Without Depression. International Journal of Geriatric Psychiatry, 26(12), 1267-1274. https://doi.org/10.1002/gps.2676
Diniz, B. S., Butters, M. A., Albert, S. M., Dew, M. A., & Reynolds, C. F. (2013). Late-Life Depression and Risk of Vascular Dementia and Alzheimer's Disease: Systematic Review and Meta-aAnalysis of Community-Based Cohort Studies. The British Journal of Psychiatry, 202(5), 329-335. https://doi.org/10.1192/bjp.bp.112.118307
Ezzati, A., Katz, M. J., Derby, C. A., Zimmerman, M. E., & Lipton, R. B. (2019). Depressive Symptoms Predict Incident Dementia in a Community Sample of Older Adults: Results From the Einstein Aging Study. Journal of Geriatric Psychiatry and Neurology, 32(2), 97-103. https://doi.org/10.1177/0891988718824036
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). Mini-Mental State. A Practical Method for Grading the Cognitive State of Patients for the Clinician. Journal of Psychiatry Research, 12(3), 189-198. https://doi.org/10.1016/0022-3956(75)90026-6
Gallagher, D., & Thompson, L. W. (1983). Depression. In P. M. Lewinshon & L. Teri (Eds.), Clinical Geropsychology: New Directions in Assessment and Treatment. Pergamon Press.
Garay, M. (2007). Relación entre Depresión y Deterioro Cognitivo [Postgraduate Thesis, Universidad Nacional de La Plata]. Repositorio Institucional de La UNLP. http://sedici.unlp.edu.ar/handle/10915/5482
Díaz, E. G. (2018). Prevalencia de depresión en el Adulto Mayor Institucionalizado [Undergraduate Thesis, Universidad de La Laguna]. https://riull.ull.es/xmlui/bitstream/handle/915/11024/Prevalencia%20de%20depresion%20en%20el%20adulto%20mayor%20institucionalizado.pdf?sequence=1
Harrison, R., Savla, N., & Kafetz, K. (1990). Dementia, Depression and Physical Disability in a London Borough: A Survey of Elderly People in and out of Residential Care and Implications for Future Developments. Age and Ageing, 19(2), 97-103. https://doi.org/10.1093/ageing/19.2.97
Izal, M., & Montorio, I. (1993). Adaptation of the Geriatric Depression Scale in Spain: A Preliminary Study. Clinical Gerontologist, 13(2), 83-91. https://doi.org/10.1300/J018v13n02_07
Jassim, H., Tuama, A. M., & Alwan, H. (2019). Investigating of Geriatric Depression among Elderly in Nasiriyah City. Indian Journal of Public Health Research & Development, 10(4). https://doi.org/10.5958/0976-5506.2019.00770.8
Javaherian, K., Newman, B. M., Weng, H., Hassenstab, J., Xiong, C., Coble, D., Fagab, A. M., Bezinger, T., & Morris, J. C. (2019). Examining the Complicated Relationship Between Depressive Symptoms and Cognitive Impairment in Preclinical Alzheimer Disease. Alzheimer Disease & Associated Disorders, 33(1), 15-20. https://doi.org/10.1097/WAD.0000000000000284
Jerez-Roig, J., Ferreira, L. M. d. B. M., Araujo, J. R. T., & Lima, K. C. (2017). Functional decline in nursing home residents: A prognostic study. PloS One, 12(5), e0177353. https://doi.org/10.1371/journal.pone.0177353
Johansson, M., Stomrud, E., Lindberg, O., Westman, E., Johansson, P. M., van Westen, D., Mattsson, N., & Hansson, O. (2020). Apathy and Anxiety are Early Markers of Alzheimer's Disease. Neurobiology of Aging, 85, 74-82. https://doi.org/10.1016/j.neurobiolaging.2019.10.008
Kim, H.-J., Kim, B.-H., & Kim, O.-S. (2011). The Effect of Visual and Hearing Impairment on Depression and Cognitive Function in Community-Dwelling Elderly: The Korean Longitudinal Study of Aging 2008. Korean Journal of Adult Nursing, 23(6), 584-594.
Landi, F., Onder, G., Cesari, M., Barillaro, C., Lattanzio, F., Carbonin, P. U., & Bernabei, R. (2004). Comorbidity and Social Factors Predicted Hospitalization in Frail Elderly Patients. Journal of Clinical Epidemiology, 57(8), 832-836. https://doi.org/10.1016/j.jclinepi.2004.01.013
Leung, M.-y., Wang, C., & Wei, X. (2020). Structural Model for the Relationships Between Indoor Built Environment and Behaviors of Residents with Dementia in Care and Attention Homes. Building and Environment, 169, 106532. https://doi.org/10.1016/j.buildenv.2019.106532
Li, J. (2020). Elderly Suicide. A Study on Suicide (pp. 181-213). Springer. https://doi.org/10.1007/978-981-13-9499-7
Lichtenberg, P. A., Ross, T., Millis, S. R., & Manning, C. A. (1995). The Relationship Between Depression and Cognition in Older Adults: A Cross-Validation Study. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 50(1), 25-32. https://doi.org/10.1093/geronb/50B.1.P25
Lobo, A., Ezquerra, J., Gómez, F. B., Sala, J., & Seva, A. D. (1979). Cognocitive Mini-Test (A Simple Practical Test to Detect Intellectual Changes in Medical Patients). Actas Luso-Espanolas de Neurologia, Psiquiatria y Ciencias Afines, 7(3), 189-202.
Loughrey, D. G., Pakhomov, S. V., & Lawlor, B. A. (2020). Altered Verbal Fluency Processes in Older Adults with Age-Related Hearing Loss. Experimental Gerontology, 130, 110794. https://doi.org/10.1016/j.exger.2019.110794
Llinás, J., Villalta, J., & López-Pousa, S. (1991). CAMDEX Adaptación y Validación Españolas. Áncora.
McDermott, L. M., & Ebmeier, K. P. (2009). A Meta-Analysis of Depression Severity and Cognitive Function. Journal of Affective Disorders, 119(1-3), 1-8. https://doi.org/10.1016/j.jad.2009.04.022
Modrego, P. J., & Ferrández, J. (2004). Depression in Patients with Mild Cognitive Impairment Increases the Risk of Developing Dementia of Alzheimer Type: A Prospective Cohort Study. Archives of Neurology, 61(8), 1290-1293. https://doi.org/10.1001/archneur.61.8.1290
Murphy, E. (1986). Affective disorders in the elderly: Churchill Livingstone.
Olivera, J., Benabarre, S., Lorente, T., Rodríguez, M., Pelegrín, C., Calvo, J. M., Leris, J. M., Idánez, D., & Arnal, S. (2008). Prevalence of Psychiatric Symptoms and Mental Disorders Detected in Primary Care in an Elderly Spanish Population. The PSICOTARD Study: preliminary findings. International Journal of Geriatric Psychiatry: A Journal of the Psychiatry of Late Life and Allied Sciences, 23(9), 915-921. https://doi.org/10.1002/gps.2004
Panza, F., Frisardi, V., Capurso, C., D'Introno, A., Colacicco, A. M., Imbimbo, B. P., … Pilotto, A. (2010). Late-Life Depression, Mild Cognitive Impairment, and Dementia: Possible Continuum? The American Journal of Geriatric Psychiatry, 18(2), 98-116. https://doi.org/10.1097/JGP.0b013e3181b0fa13
Paterniti, S., Verdier-Taillefer, M.-H., Dufouil, C., & Alpérovitch, A. (2002). Depressive Symptoms and Cognitive Decline in Elderly People: Longitudinal Study. The British Journal of Psychiatry, 181(5), 406-410. https://doi.org/10.1192/bjp.181.5.406
Péquignot, R., Dufouil, C., Pérès, K., Artero, S., Tzourio, C., & Empana, J. P. (2019). Depression Increases the Risk of Death Independently From Vascular Events in Elderly Individuals: The Three”City Study. Journal of the American Geriatrics Society, 67(3), 546-552. https://doi.org/10.1111/jgs.15731
Plati, M. C. F., Covre, P., Lukasova, K., & Macedo, E. C. d. (2006). Depressive Symptoms and Cognitive Performance of the Elderly: Relationship Between Institutionalization and Activity Programs. Brazilian Journal of Psychiatry, 28(2), 118-121. https://doi.org/10.1590/S1516-44462006000200008
Prakash, A. (2019). Psychology of Depression in Elderly: A Review. EC Psychology and Psychiatry, 8, 263-272.
Rabbitt, P., Donlan, C., Watson, P., McInnes, L., & Bent, N. (1995). Unique and Interactive Effects of Depression, Age, Socioeconomic Advantage, and Gender on Cognitive Performance of Normal Healthy Older People. Psychology and Aging, 10(3), 307-313. https://doi.org/10.1037/0882-7974.10.3.307
Ray, S., & Agarwal, P. (2020). Depression and Anxiety in Parkinson Disease. Clinics in Geriatric Medicine, 36(1), 93-104. https://doi.org/10.1016/j.cger.2019.09.012
Rodríguez, P. R. (1998). El Problema de la Dependencia en las Personas Mayores. Documentación Social, 112, 33-64.
Ruthirakuhan, M., Herrmann, N., Vieira, D., Gallagher, D., & Lanctôt, K. L. (2019). The Roles of Apathy and Depression in Predicting Alzheimer Disease: A Longitudinal Analysis in Older Adults With Mild Cognitive Impairment. The American Journal of Geriatric Psychiatry, 27(8), 873-882. https://doi.org/10.1016/j.jagp.2019.02.003
Sánchez, I. (1999). Depresión, deterioro cognitivo y demencia: unas relaciones polémicas.Revista Española de. Geriatría y Gerontología,34(3), 123-124.
Sakurai, R., & Okubo, Y. (2020). Depression, Fear of Falling, Cognition and Falls. In M. Montero-Odasso, & R. Camicioli (Eds.), Falls and Cognition in Older Persons (pp. 49-66). Springer. https://doi.org/10.1007/978-3-030-24233-6
Schoevers, R., Beekman, A., Deeg, D., Jonker, C., & Tilburg, W. V. (2003). Comorbidity and Risk”Patterns of Depression, Generalised Anxiety Disorder and Mixed Anxiety-Depression in Later Life: Results from the AMSTEL Study. International Journal of Geriatric Psychiatry, 18(11), 994-1001. https://doi.org/10.1002/gps.1001
Selbæk, G., Engedal, K., & Bergh, S. (2013). The Prevalence and Course of Neuropsychiatric Symptoms in Nursing Home Patients With Dementia: A Systematic Review. Journal of the American Medical Directors Association, 14(3), 161-169. https://doi.org/10.1016/j.jamda.2012.09.027
Singh, M. K., & Lee, A. G. (2019). Visual Loss and Depression. In H. Beaver, & A. G. Lee (Eds.), Geriatric Ophthalmology (pp. 73-80). Springer. https://doi.org/10.1007/978-3-030-04019-2
Snowdon, J. (1990). The Prevalence of Depression in Old Age. International Journal of Geriatric Psychiatry, 5(3), 141-144. https://doi.org/10.1002/gps.930050302
Taivalantti, M., Barnett, J. H., Halt, A.-H., Koskela, J., Auvinen, J., Timonen, M., Järvelin M. R. , & Veijola, J. (2020). Depressive Symptoms as Predictors of Visual Memory Deficits in Middle-Age. Journal of Affective Disorders, 264, 29-34. https://doi.org/10.1016/j.jad.2019.11.125
Tan, E. Y., Köhler, S., Hamel, R. E., Muñoz-Sánchez, J. L., Verhey, F. R., & Ramakers, I. H. (2019). Depressive Symptoms in Mild Cognitive Impairment and the Risk of Dementia: A Systematic Review and Comparative Meta-Analysis of Clinical and Community-Based Studies. Journal of Alzheimer's Disease, 67(4), 1319-1329. https://doi.org/10.3233/JAD-180513
Tarugu, J., Pavithra, R., Vinothchandar, S., Basu, A., Chaudhuri, S., & John, K. (2019). Effectiveness of Structured Group Reminiscence Therapy in Decreasing the Feelings of Loneliness, Depressive Symptoms and Anxiety Among Inmates of a Residential Home for the Elderly in Chittoor District. International Journal of Community Medicine And Public Health, 6(2), 847-854. http://dx.doi.org/10.18203/2394-6040.ijcmph20190218
Valvanne, J., Juva, K., Erkinjuntti, T., & Tilvis, R. (1996). Major Depression in the Elderly: A Population Study in Helsinki. International Psychogeriatrics, 8(3), 437-443. https://doi.org/10.1017/S1041610296002797
Wilson, R. S., Barnes, L., De Leon, C. M., Aggarwal, N., Schneider, J., Bach, J., Pilat, J., Beckett, L. A., Arnold, S. E., Evans, D., & Bennett, D. A. (2002). Depressive Symptoms, Cognitive Decline, and Risk of AD in Older Persons. Neurology, 59(3), 364-370. https://doi.org/10.1212/WNL.59.3.364
Won, K.-A., & Kim, J.-R. (2019). Effects of Cognitive-Health Improvement Group Program Combined with Lifestyle Education on Cognitive Function and Depression for the Elderly Korean People Using Rural Senior Center. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 15(7), 1576-1577.
Wu, Y., Ma, Q., Sun, H.-P., Xu, Y., Niu, M.-E., & Pan, C.-W. (2017). Myopia and Depressive Symptoms Among Older Chinese Adults. PloS One, 12(5), e0177613. https://doi.org/10.1371/journal.pone.0177613
Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1982). Development and Validation of a Geriatric Depression Screening Scale: a Preliminary Report. Journal of Psychiatric Research, 17(1), 37-49.
Zunzunegui, M., Béland, F., Gornemann, I., & Del Ser, T. (1999). La Depresión como Factor Predictor del Deterioro Cognitivo en las Personas Mayores. Revista Española de Geriatría y Gerontología, 34(3), 125-134.
Zunzunegui, M. V., Beland, F., Llacer, A., & Leon, V. (1998). Gender Differences in Depressive Symptoms Among Spanish Elderly. Social Psychiatry and Psychiatric Epidemiology, 33(5), 195-205. https://doi.org/10.1007/s001270050043
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