Reproductive, therapeutic and social human cloning
DOI:
https://doi.org/10.26512/rbb.v1i2.8069Keywords:
Human cloning. Reproductive cloning. Therapeutic cloning. Social cloning. Bioethics. Human Rights.Abstract
The term “cloning” has been used in many different ways. That can be undertaken for reproductive or therapeutic purposes. We present the circumstances that would justify those kinds of cloning as well as medical, legal and social objections related to these practices. We also discuss the impact of cloning in the manufacturing of biopharmaceutical products, including its limitations and advantages. At last, the article makes ethical and social considerations about this topic, its perspectives and ethical limits. The study denounces the social cloning that can be found in the reproduction of the genocide of the poor (“poorcide”) and also the dangerous homogenization made possible by the massive communication technology which intends to teach us how to live with the unacceptable.
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References
BREM, G. & KUHHOLZER, B. The recent history of somatic cloning in mammals. Cloning Stem Cells 4(1): 57-63, 2002.
CIBELLI, J. B; KIESSLING, A. A.; CUNIFF, K.; RICHARDS, C.; LANZA, R., P. & WEST, M.D. Somatic cell nuclear transfer in humans: pronuclear and early embryonic development. The J. of Regenerative Medicine 2: 25-31, 2001.
CIBELLI, J.B.; GRANT, K. A.; CHAPMAN, K. B.; CUNNIFF, K.; WORST, T.; GREEN, H. L.; WALKER, S. J.; GUTIN, P. H,; VILNER, L,; TABAR, V.; DOMINKO, T.; KANE, J., WETTSTEIN, P.J.; LANZA, R. P.; STUDER, L.; VRANA, K. E. & WEST, M. D. Partenogenetic stem cells in nonhuman primates. Science 1, 295 (5556): 819, 2002.
COLMAN, A. Dolly, Polly and other ¢ollys¢: likely impact of cloning technology on biomedical uses of livestock. Genet Anal, 15 (3-5): 167-173, 1999.
COLMAN, A. & KIND, A. Therapeutic cloning. Concepts and practicalities. Trends Biotechnol 18(5): 192-196, 2000.
EVANS, M. J.; GURER, C.; LOIKE, J. D.; WILMUT, I.; SCHINIEKE, A. E. & SCHON, E. A. Mitochondrial DNA genotypes in nuclear transfer-drived cloned sheep. Nat Genet 23 (1): 90-93, 1999.
GURDON, J. B. The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. J. Embrión Exp. Morphol. 10: 622-640, 1962
GURDON, J. B.; LASKEY, R. A. & REEVES, O. R. The developmental capacity of nuclei transplanted from keratinized skin cells of adult frogs. J. Embryol. Exp. Morph, 34: 93-112, 1975.
HOSAKA, K.; OHI, S.; ANDO, A.; KOBAYASHI, M. & SATO, K. Cloned mice derived from somatic cell nuclei. Hum. Cell, 13(4): 237-242, 2000.
MAIAENSCHEIN, J. On cloning: advocating history of biology in the public interest. J. Hist. Biol, 34(3): 423-432, 2001.
McGRATH, J. & SOLTHER, D. Inability of mouse blastomere nuclei transferred to enucleated zygotes to support development in vitro. Science, 226: 1317-
, 1984.
MOLLARD, R., DENHAM, M.; TROUNSON, A. Technical advances and pitfalls on the way to human cloning. Differentation, 70(1): 1-9, 2002.
PERRY, A. C. & WAKAYAMA, T. Ultimately ends and new begginings in mouse cloning. Nat. Genet, 30: 243- 244, 2002.
POLEJAEVA, I. A.; CHEN, S. H.; VAUGTH, T. D.; PAGE, R. L.; MULLINS, J.; BALL, S.; DAI, V.; BOONE, J.; WEALKER, S.; AYARES, D. L.; COLMAN, A. & CAMPBELL, K. M. S. Cloned pigs produced by nuclear transfer from adult somatic cells. Nature, 407: 86-90, 2000.
RIDEOUT, W. M.; HOCHEDLINGER, K.; KYBA, M.; DALEY, G. Q. & JAENISCH, R. Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell, 108: 645-656, 2002.
THOMSON, J. A.; ITSKOVITZ-ELDOR, J.; SHAPIRO, S. S.; WAKNITZ, M. A.; SWIERGIEL, J. J,; MARSHALL, V. S. & JONES, J. M. Embryonic stem cell lines derived from human blastocists. Science, 282 (5391):1145-7, 1998.
TIAN, X. C.; XU, J. & YANG, X. Normal telomere lengths found in cloned cattle. Nat Genet, 26(3): 272-273, 2000.
WILMUT, I.; SCHNIEKE, A. E.; McWHIR, J.; KIND, A. J. & CAMPBELL, K. H. Viable offspring derived from fetal and adult mammalian cells. Nature, 385: 810- 813, 1997.
WOOD, P. G. To what extent can the law control human cloning?. Med. Sci. Law, 39 (1): 5-10, 1999.
